Interventions in burnout and their effects on biomarkers: A systematic review

Authors

  • Andrea Marilin Vinueza-Solórzano Pontifícia Universidade Católica de Rio de Janeiro, Rio de Janeiro, RJ, Brazil
  • Guilherme Domingos Martins Pontifícia Universidade Católica de Rio de Janeiro, Rio de Janeiro, RJ, Brazil https://orcid.org/0000-0003-0285-4969
  • Carolina Maia Siciliano Pontifícia Universidade Católica de Rio de Janeiro, Rio de Janeiro, RJ, Brazil https://orcid.org/0009-0005-4852-1205
  • Breno Sanvicente-Vieira Pontifícia Universidade Católica de Rio de Janeiro, Rio de Janeiro, RJ, Brazil https://orcid.org/0000-0002-9922-966X
  • Clarissa Pinto Pizarro de Freitas Pontifícia Universidade Católica de Rio Grande do Sul, Porto Alegre, RS, Brazil https://orcid.org/0000-0002-2274-8728
  • Jaqueline de Carvalho Rodrigues Pontifícia Universidade Católica de Rio de Janeiro, Rio de Janeiro, RJ, Brazil https://orcid.org/0000-0001-9947-4705

Abstract

Although burnout is a widely studied topic, there is still no clear consensus on its definition, and many interventions are implemented without a rigorous evaluation of their actual effectiveness. This study aimed to analyze the biomarkers associated with the response to interventions applied to adults with burnout. A systematic review was conducted using the PRISMA methodology, with searches performed on PubMed, Web of Science, PsycInfo, and Embase from April to May 2023. Six articles met the inclusion criteria for the final analysis. It was found that mindfulness-based interventions are common, with cortisol collected from saliva being the most frequently evaluated biomarker. Therefore, these interventions primarily focus on analyzing stress reduction, although this is only one precursor of burnout. This study emphasizes the importance of analyzing the impact of interventions through biomarkers and behavioral measures, assessing pre- and post-intervention, to accurately determine their overall effectiveness.

Keywords: burnout, therapy, biomarkers.

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Published

2025-04-30

Issue

Vol. 25 No. contínuo (2025): rPOT

Section

Literature Reviews

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